Graham MM, Norris CM, Galbraith PD, Knudtson ML, Ghali WA. Quality of life after coronary revascularization in the elderly. Eur Heart J 2006 July; 27(14):1690-8.

Aims: To describe health status outcomes at 4 years for a cohort of elderly patients with cardiac disease.

Methods and Results: Using the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease, an outcomes initiative capturing all patients undergoing cardiac catheterization in Alberta, Canada, health status was measured using the Seattle Angina Questionnaire (SAQ) and crude and risk-adjusted outcomes were determined and compared for patients treated with percutaneous coronary intervention or coronary artery bypass surgery (CABG) vs. medical therapy. Response rates among surviving, consenting patients were 64.8% for patients<70 years (n=7883), 77.3% for patients aged 70–79 years (n=2940), and 77.7% for patients >=80 years of age (n=439). For patients aged <70 years, and those aged 70–79 years, for all dimensions of the SAQ, scores were significantly better for patients treated with revascularization procedures than with medical therapy. For patients over the age of 80 years, scores for patients treated with CABG in particular were significantly better, with
the exception of exertional capacity. At 3 years, all scores remained stable or improved, and continued to favour revascularization.

Conclusion: Elderly patients undergoing revascularization have better health status at 4 years than do those in the same age group who do not undergo revascularization. These findings suggest that age should not deter against revascularization given the combined survival and quality-of-life benefits.

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